Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers
نویسندگان
چکیده
منابع مشابه
Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers12
In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes. We identified Mcl-1 (myeloid cell leukemia-1), an anti-apoptotic member of the Bcl-2 family, as a target for sensitizing pancreatic cancer cells to chemoradiation. In the present study we investigated Mcl-1 inhibition by ei...
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ژورنال
عنوان ژورنال: Translational Oncology
سال: 2015
ISSN: 1936-5233
DOI: 10.1016/j.tranon.2014.12.004